Hongyi Zhang achieved Ph.D. in immunology from Southeast University in 2015, and from 2013 to 2018, he co-trained doctoral and postdoctoral fellow at Yale University. He focused on brain metastasis and its microenvironment.

Hongyi Zhang  ph.D.

Associated Professor

Main research directions :

1. Molecular mechanisms of tumor stem cells in brain metastasis of tumors

2. Mutual regulatory mechanisms between the brain microenvironment and brain metastatic tumors

3. Targeted therapy and immunotherapy strategies for brain tumors

Representative academic achievements：

1.《Brain metastasis》2026 Shanghai Science and Technology Press

2. Secreted clusterin inhibits tumorigenesis by modulating tumor cells and macrophages in human meningioma.

Neuro-Oncology 2024,26(7), 1262–1279.

3. Global analysis of HLA-A2 restricted MAGE-A3 tumor antigen epitopes and corresponding TCRs in non-small cell lung cancer.

Theranostics(2023) 13(13):4449-4468.

4. LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy. Nature Cell Biology(2020)22:1276–128.

Main academic positions:

1. International Society of Respiratory Sciences - Young Scholar Award

2. Member of the 4th Clinical Application Committee of Pharmaceutical Biotechnology of China Pharmaceutical Biotechnology Association

3. Medical Association Member of the Chinese Society of Pathophysiology

E-mail：hongyizhang@jnu.edu.cn