Junhong Luo Ph.D., Professor and Ph.D. Supervisor at Jinan University. He is a Young Talent of the National High-Level Talent Recruitment Program for Overseas Talents, a Distinguished Young Scholar under the National Natural Science Foundation of China, and a High-Level Talent introduced under the Guangdong Pearl River Talent Program. Prior to returning to China, he served as a tenured Research Scientist at the Commonwealth Scientific and Industrial Research Organisation (CSIRO) of Australia. His main research interests include bioinformatics, multi-omics, and artificial intelligence. He has published more than 30 academic papers in top-tier journals including Cell, Nature, Nature Aging, Nature Genetics, Nature Protocols, Nature Communications, Science Advances, and STTT.

Main research directions :

Bioinformatics, Artificial intelligence, Immunology, Multi-omics

Representative publications:

Wenpu Lai; Yangqiu Li; Oscar Junhong Luo. (2025). MIST: an interpretable and flexible deep learning framework for single-T cell transcriptome and receptor analysis, Science Advances, 11(14), adr7134. IF=12.5

Yang Y*, Xiao C*, Zou D*, Wang L*, … , Chen G#, Li T#, Luo OJ#, Jiang W#. (2025). Deep learning-enabled multiphoton microscopy predicts colorectal cancer recurrence from routine FFPE specimens. NPJ Digit Med. 8(1):689. IF=15.1

Wenpu Lai*, Qiuyue Feng*, Wen Lei*, … , Hao Wang#, Zhenhua Li#, Guobing Chen#, Oscar Junhong Luo#. (2025). Deciphering Immunosenescence From Child to Frailty: Transcriptional Changes, Inflammation Dynamics, and Adaptive Immune Alterations, Aging Cell, 24(7):e70082. IF=7.1

Ai R*, Mao L*, Jin X*, Campos-Marques C*, … , Silva JM#, Luo OJ#, Fang EF#. (2025) NAD+ reverses Alzheimer‘s neurological deficits via regulating differential alternative RNA splicing of EVA1C. Science Advances. 11(45):eady9811. IF=12.5

Li, Xiaobo*; Yan, Sishan*; Wu, Xiaoyu*; …, Luo, Oscar Junhong#; Zhang, Dongmei#; Ye, Wencai#; Chen, Minfeng#. (2025) Pericytes promote metastasis by regulating tumor local vascular tone and hemodynamics, Nature Communications, 16(1): 7115. IF=15.7

Xiao Yang*, Yalei Wen*, Shengying Qin*, Yang Zhou*, … , Oscar Junhong Luo#, Xiangchun Shen#, Rutao Cui#, Tongzheng Liu#. (2025). UFMylation maintains tumor suppressor pVHL stability by activating the deubiquitinase BAP1, Science Advances, 11(28), adt8800. IF=12.5

Chao Ke*; Boya Huang*; Jian Xiang*; Jinlian Liang*; … ; Guobing Chen#; Oscar Junhong Luo#; Hongyi Zhang#. (2024) Secreted Clusterin Inhibits Tumorigenesis by Modulating Tumor Cell and Macrophage in Human Meningioma, Neuro-Oncology, 26(noae034) IF=13.4

Bei Zhang*, Zhiyao Ren*, Jianfu Zhao*, Yue Zhu*, … , Hongyi Zhang#, Guobing Chen#, Oscar Junhong Luo#. (2023). Global analysis of HLA-A2 restricted MAGE-A3 tumor antigen epitopes and corresponding TCRs in non-small cell lung cancer. Theranostics, 13(13):4449-4468. IF=13.3

Xiao, C., Ren, Z., Zhang, B., Mao, L., Zhu, G., … Zhang, H., Wang, P.#, Liang, X.#, Luo, O.J.#, Chen, G.#. (2023). Insufficient epitope-specific T cell clones are responsible for impaired cellular immunity to inactivated SARS-CoV-2 vaccine in older adults. Nature Aging, 3(3) IF=19.4

Luo, O. J*#., Lei, W.*, Zhu, G.*, Ren, Z.*, … , Chen, G. (2022). Multidimensional single-cell analysis of human peripheral blood reveals characteristic features of the immune system landscape in aging and frailty. Nature Aging, 2(4), 348–364. IF=19.4

Di, B.*, Jia, H.*, Luo, O. J.*, Lin, F.*, Li, K., Zhang, Y., Wang, H., Liang, H., Fan, J., & Yang, Z. (2020). Identification and validation of predictive factors for progression to severe COVID-19 pneumonia by proteomics. Signal Transduction and Targeted Therapy, 5(1), 217. IF=52.7

Li, X.*, Luo, O. J.*, … , Ruan, Y. (2017). Long-read ChIA-PET for base-pair-resolution mapping of haplotype-specific chromatin interactions. Nature Protocols, 12(5), 899–915. IF=16.0

Tang, Z.*, Luo, O. J.*, Li, X.*, … , Ruan, Y. (2015). CTCF-Mediated Human 3D Genome Architecture Reveals Chromatin Topology for Transcription. Cell, 163(7), 1611–1627. IF=42.5

*Co-first  #Co-correspondence

E-mail：luojh@jnu.edu.cn